1589571-77-6
中文名稱
化合物 T33815
英文名稱
BPN-13661
CAS
1589571-77-6
分子式
C18H20Cl2N4O2S
分子量
427.34
MOL 文件
1589571-77-6.mol
1589571-77-6 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
ORC-13661, also known as BPN-13661, is a Potent, Well Tolerated and Orally Active Protective Agents Against Aminoglycoside-Induced Hearing Loss. ORC-13661 protects mechanosensory hair cells with HC50 of 120 nM and demonstrated 100% protection in the zebrafish assay, superior physiochemical and pharmacokinetic and toxicologic properties as well as complete in vivo protection in rats. ORC-13661 is being developed by Oricula Therapeutics.