161442-19-9
中文名稱
N4-苯甲酰基-5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺
英文名稱
N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite
CAS
161442-19-9
分子式
C46H51FN5O8P
分子量
851.9
MOL 文件
161442-19-9.mol
更新日期
2026/05/12 10:20:43
161442-19-9 結(jié)構(gòu)式
基本信息
中文別名
2-F-RC(N-BZ) 亞磷酰胺單體N4-苯甲?；?5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺
N-苯甲?；?5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脫氧-2'-氟胞苷 3'-[2-氰基乙基 N,N-二異丙基氨基亞磷酸酯
N-苯甲?；?5'-O-[二(4-甲氧基苯基)苯基甲基]-2'-脫氧-2'-氟胞苷 3'-[2-氰基乙基 N,N-二異丙基氨基亞磷酸酯]
(2R,3R,4R,5R)-5-(4-BENZAMIDO-2-OXOPYRIMIDIN-1(2H)-YL)-2-((BIS(4-METHOXYPHENYL)(PHENYL)METHOXY)METHYL)-4-FLUOROTETRAHYDROFURAN-3-YL (2-CYANOETHYL) DIISOPROPYLPHOSPHORAMIDITE
英文別名
Bz-2'-F-dC PhosphoramiditeN4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine phosphoramidite
N4-Benzoyl-2'-deoxy-5'-O-DMT-2'-fluoro-cytidine 3-CE phosphoramidite
2''-Fluoro-n4-benzoyl-5''-o-dmt-2''-deoxycytidine-3''-ce-phosphoramidite
N4-benzoyl-5'-O-(4, 4'-dimethoxytrityl)-2'-fluoro-2'-deoxycytidine-3'-CE-Phosphoramidite
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluorocytidine 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
Cytidine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-2'-deoxy-2'-fluoro-, 3'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]
所屬類別
醫(yī)藥中間體：原料藥中間體物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : 100 mg/mL (117.38 mM; Need ultrasonic)
酸度系數(shù)(pKa)8.50±0.20(Predicted)
形態(tài)Solid
顏色White to light yellow
InChIKeyDBKYISAGLSNHRB-VDQODKCANA-N
SMILESC(NC1C=CN([C@H]2[C@H](F)[C@H](OP(OCC)N(C(C)C)C(C#N)(C)C)[C@@H](COC(C3=CC=C(OC)C=C3)(C3=CC=C(OC)C=C3)C3=CC=CC=C3)O2)C(=O)N=1)(=O)C1=CC=CC=C1 |&1:6,7,9,24,r|
常見問題列表
用途
N4-苯甲酰基-5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺是一種熒光寡核苷酸RNA探針，也用于提高代謝穩(wěn)定性和誘導(dǎo)有效的RNAi介導(dǎo)的基因沉默。
N4-苯甲?；?5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺價(jià)格(試劑級)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-138577 | N4-苯甲?；?5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺 2'-F-Bz-dC Phosphoramidite | 161442-19-9 | 100 mg | 192元 |
| 2026/06/05 | HY-138577 | N4-苯甲?；?5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺 2'-F-Bz-dC Phosphoramidite | 161442-19-9 | 250 mg | 342元 |
| 2025/05/22 | HY-138577 | N4-苯甲?；?5'-O-DMT-2'-氟-脫氧胞苷-3'-氰乙氧基亞磷酰胺 2'-F-Bz-dC Phosphoramidite | 161442-19-9 | 10 mM * 1 mLin DMSO | 211元 |