167114-91-2
中文名稱
AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE
英文名稱
AUTOCAMTIDE-2-RELATED INHIBITORY PEPTIDE
CAS
167114-91-2
分子式
C64H116N22O19
分子量
1497.74
MOL 文件
167114-91-2.mol
更新日期
2026/06/01 19:17:35
167114-91-2 結(jié)構(gòu)式
基本信息
中文別名
[ALA9] AUTOCAMTIDE 2肽 英文別名
ALPILC
CCL27
ESKINE
Alk Phos
FLJ10774
Skinkine
CTACK HUMAN
DKFZp434C116
KKALRRQEAVDAL
所屬類別
生物：ELISA 試劑盒物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C
溶解度H2O: soluble
溶解度可溶于水中
形態(tài)lyophilized powder
顏色white
生物來源synthetic
水溶解性Soluble to 1 mg/ml in water
InChIKeyCOEHZSYVSXUBHI-CYZNULJVSA-N
安全數(shù)據(jù)
危險(xiǎn)品標(biāo)志Xn,F
危險(xiǎn)類別碼20/21/22-36-11
WGK Germany3
WGK Germany3
存儲(chǔ)類別11 - Combustible Solids
常見問題列表
生物活性
Autocamtide-2-related inhibitory peptide 是高度特異性的、CaMKII 的有效抑制劑，其IC50 值為 40 nM。靶點(diǎn)
IC50: 40 nM (CaMKII).
體外研究
It is found that Autocamtide-2-related inhibitory peptide (a novel synthetic peptide ATP) is a potent inhibitor of CaM-kinase II with an IC 50 of 40 nM, which is active in the presence or absence of Ca 2+ /calmodulin. It is 50 and 500 times more potent than CaMK-(281-302Ala286) and KN-93,respectively, under the assay condition used.