171783-05-4
中文名稱
171783-05-4
英文名稱
CROSSTIDE
CAS
171783-05-4
分子式
C48H77N17O17
分子量
1164.23
MOL 文件
171783-05-4.mol
更新日期
2026/05/28 12:40:48
171783-05-4 結(jié)構(gòu)式
基本信息
中文別名
模擬肽CROSSTIDE 英文別名
Crosstide >=97% (HPLC), lyophilized powderGlycine, glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-phenylalanyl-L-alanyl-L-α-glutamyl-
Glycine, glycyl-L-arginyl-L-prolyl-L-arginyl-L-threonyl-L-seryl-L-seryl-L-phenylalanyl-L-alanyl-L-a-glutaMyl-
所屬類別
生物化工：多肽物理化學(xué)性質(zhì)
儲(chǔ)存條件−20°C
溶解度在水中可溶
形態(tài)凍干粉
顏色White to off-white
序列Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly
模擬肽CROSSTIDE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-P0315 | 模擬肽CROSSTIDE Crosstide | 171783-05-4 | 1 mg | 1100元 |
| 2026/06/05 | HY-P0315 | 模擬肽CROSSTIDE Crosstide | 171783-05-4 | 5 mg | 3300元 |
| 2026/06/05 | HY-P0315 | 模擬肽CROSSTIDE Crosstide | 171783-05-4 | 10 mg | 5115元 |
常見問(wèn)題列表
生物活性
Crosstide 是一種糖原合成酶激酶α/β融合蛋白序列的模擬肽，是 Akt 的底物。靶點(diǎn)
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Akt
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體外研究
16HBE14o? cells exposed to RV39 demonstrate a crosstide kinase activity in vitro. Serine phosphorylation of crosstide is confirmed by immunoblotting, and phosphorylation is blocked by PP2 but not by PP3. The wildtype GST-AKT2 shows significant phosphoryl transferase activity towards crosstide, reaching an initial velocity of 16 pmol phosphate/min/μg enzyme. The mutant GST-AKT2T/E,S/D displayed an initial velocity of 85 pmol phosphate/min/μg kinase for phosphorylation of Crosstide, corresponding to a 5-fold increase compared to the wildtype enzyme.