1879-77-2
中文名稱
多倍他索
英文名稱
doxibetasol
CAS
1879-77-2
分子式
C22H29FO4
分子量
376.465
MOL 文件
1879-77-2.mol
更新日期
2026/05/18 11:11:06
1879-77-2 結(jié)構(gòu)式
基本信息
中文別名
多倍他索多倍他索雜質(zhì)
21-脫氧倍他米松
倍他米松戊酸酯雜質(zhì)B(EP)
9Α-氟-16Β-甲基孕甾-1,4-二烯-11Β,17Α-二醇-3,20-二酮
英文別名
doxibetasol21-Deoxy Betamethasone
Betamethasone Valerate EP Impurity B
9-Fluoro-16-methylpregna-1,4-diene-11,17-diol-3,20-dione
9-Fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
16β-methyl-9α-fluoro-11β,17α-dihydroxy-1,4-pregnadiene-3,20-dione
16β-Methyl-11β,17-dihydroxy-9-fluoro-5α-pregnane-1,4-diene-3,20-dione
Betamethasone Valerate impurity 1/Betamethasone Valerate EP Impurity B/Doxybetasol/21-Deoxy Betamethasone
(8S,9R,10S,11S,13S,14S,16S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
(8S,9R,10S,11S,13S,14S,16S,17R)-17-ethanoyl-9-fluoro-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
物理化學(xué)性質(zhì)
外觀性狀結(jié)晶（氯仿）。熔點(diǎn)230-234℃。
熔點(diǎn)232-234 °C(Solv: chloroform (67-66-3))
沸點(diǎn)527.1±50.0 °C(Predicted)
密度1.25±0.1 g/cm3(Predicted)
溶解度Acetone (Slightly), Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
酸度系數(shù)(pKa)12.52±0.70(Predicted)
形態(tài)Solid
顏色White to Pale Yellow