1894207-45-4
中文名稱
(S)-2-(((4'-(TRIFLUOROMETHYL)-[1,1'-BIPHENYL]-4-YL)METHYL)AMINO)PROPANAMIDE METHANESULFONIC ACID
英文名稱
KDS2010
CAS
1894207-45-4
分子式
C18H21F3N2O4S
分子量
418.43
MOL 文件
1894207-45-4.mol
更新日期
2026/03/16 15:17:18
1894207-45-4 結構式
基本信息
中文別名
化合物 KDS2010 MESYLATE(S)-2-(((4'-(TRIFLUOROMETHYL)-[1,1'-BIPHENYL]-4-YL)METHYL)AMINO)PROPANAMIDE METHANESULFONIC ACID
英文別名
KDS2010應用領域
用途一
KDS2010 is a potent, highly selective, and reversible MAO-B inhibitor which shows 12,500-fold selectivity over MAO-A. KDS2010 overcomes the disadvantages of the irreversible MAO-B inhibitor and significantly attenuates increased astrocytic GABA levels and astrogliosis, thereby enhancing synaptic transmission, and rescuing learning and memory impairments in APP/PS1 mice.