1924596-31-5
中文名稱
MAL-AMIDO-PEG8-TFP ESTER
英文名稱
Mal-amido-PEG8-TFP ester
CAS
1924596-31-5
分子式
C32H44F4N2O13
分子量
740.69
MOL 文件
1924596-31-5.mol
更新日期
2024/07/23 22:48:56
1924596-31-5 結(jié)構(gòu)式
基本信息
中文別名
馬來酰亞胺-八聚乙二醇-四氟苯酯馬來酰亞胺-酰胺-八聚乙二醇-四氟苯酚酯
馬來酰亞胺-酰胺-八聚乙二醇-四氟苯基酯
英文別名
Mal-NH-PEG8-TFPMal-amido-PEG8-TFP ester
4,7,10,13,16,19,22,25-Octaoxa-28-azahentriacontanoic acid, 31-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-29-oxo-, 2,3,5,6-tetrafluorophenyl ester
物理化學(xué)性質(zhì)
沸點780.6±60.0 °C(Predicted)
密度1.292±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)15.01±0.46(Predicted)
應(yīng)用領(lǐng)域
用途一
Mal-amido-PEG8-TFP ester is PEG linker containing a maleimide and TFP ester end group. Maleimide groups are reactive with thiols between pH 6.5 and 7.5. The TFP ester can react with primary amine groups and is also less susceptible to undergo hydrolysis compared to NHS ester. The hydrophilic PEG chains increase the water solubility of a compound in aqueous media. Longer PEG chains have improved water solubility relative to shorter PEG chains.