195875-69-5
中文名稱
化合物 T26364
英文名稱
8-Azabicyclo[3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-, (1R,2R,3S,5S)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:)
CAS
195875-69-5
分子式
C22H29Cl2NO8
分子量
506.37
MOL 文件
195875-69-5.mol
195875-69-5 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26364 英文別名
GSK372475GSK 372475
GSK-372475
NS-2359 citrate
8-Azabicyclo[3.2.1]octane, 3-(3,4-dichlorophenyl)-2-(methoxymethyl)-8-methyl-, (1R,2R,3S,5S)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:)
應(yīng)用領(lǐng)域
用途一
NS-2359 is a serotonin-norepinephrine-dopamine reuptake inhibitor. It was under development by GlaxoSmithKline (GSK) as an antidepressant, but was discontinued in 2009 when phase II clinical trials turned up disappointing results and did not support further effort by the company. NS-2359 was also in clinical trials for the treatment of ADHD, phase II having been completed in 2007. A trial exploring the effect of NS-2359 on cocaine-experienced individuals is currently ongoing.