201608-14-2
中文名稱
AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素
英文名稱
AC-DEVD-AFC
CAS
201608-14-2
分子式
C30H34F3N5O13
分子量
729.61
MOL 文件
201608-14-2.mol
更新日期
2026/05/28 12:40:48
201608-14-2 結(jié)構(gòu)式
基本信息
中文別名
CASPASE 3/7熒光底物AC-DEVD-AFC 綠胱天蛋白酶CASPASE 3/7熒光底物AC-DEVD-AFC 綠
AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素
英文別名
AC-DEVD-AFCAC-DEVD-AFC?, >98%
AC-DEVD-AFC USP/EP/BP
AC-ASP-GLU-VAL-ASP-AFC
CASPASE-3 SUBSTRATE (AFC)
M.W. 729.62 C30H34F3N5O13
CASPASE-3 FLUOROGENIC SUBSTRATE
CASPASE-3 SUBSTRATE VII, FLUOROGENIC
FLUOROGENIC CASPASE 3 SUBSTRATE AC-DEVD-AFC
CASPASE 3 (APOPAIN) SUBSTRATE 1F, FLUOROGENIC
所屬類別
生物化工：多肽物理化學(xué)性質(zhì)
沸點(diǎn)1152.7±65.0 °C(Predicted)
密度1.495±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C
溶解度H2O: 1 mg/mL
酸度系數(shù)(pKa)4.09±0.10(Predicted)
形態(tài)powder
顏色white
水溶解性H2O: 1mg/mL
序列N-Acetyl-Asp-Glu-Val-Asp-7-amido-4-trifluoroMethylcoumarin
InChIKeyGZDRODOYEFEHGG-NUDCOPPTSA-N
SMILESCC(C)[C@H](NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(O)=O)NC(C)=O)C(=O)N[C@@H](CC(O)=O)C(=O)Nc1ccc2c(OC(=O)C=C2C(F)(F)F)c1
AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | HY-P1005 | AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素 Ac-DEVD-AFC | 201608-14-2 | 1mg | 600元 |
| 2025/12/22 | HY-P1005 | AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素 Ac-DEVD-AFC | 201608-14-2 | 5mg | 1500元 |
| 2025/12/22 | HY-P1005 | AC-ASP-GLU-VAL-ASP-7-氨基-4-三氟甲基香豆素 Ac-DEVD-AFC | 201608-14-2 | 10mg | 2400元 |
常見問題列表
生物活性
Ac-DEVD-AFC 是一種熒光底物 (λex=400 nm, λem=530 nm)。體外研究
After incubation with Ac-DEVD-AFC for 1 hour, significant increase of caspase-3 activity is observed at 4 hour compare with control. There are no significant increases of caspase-3 activity in Photofrin and LPLI group. The cleavage of Ac-DEVD-AFC in response to caspase-3 activation is remarkably inhibited by shRNA-BimL transfection.