20299-15-4
中文名稱
5-Methoxycarbonylmethyl-2-thiouridine
英文名稱
5-Methoxycarbonylmethyl-2-thiouridine
CAS
20299-15-4
分子式
C12H16N2O7S
分子量
332.33
MOL 文件
20299-15-4.mol
更新日期
2026/05/09 09:09:01
20299-15-4 結構式
基本信息
英文別名
5-Methoxycarbonylmethyl-2-thiouridine2-thio-5-<(methylcarboxy)methyl>uridine
5-Pyrimidineacetic acid, 1,2,3,4-tetrahydro-4-oxo-1-β-D-ribofuranosyl-2-thioxo-, methyl ester
物理化學性質
InChIInChI=1/C12H16N2O7S/c1-20-7(16)2-5-3-14(12(22)13-10(5)19)11-9(18)8(17)6(4-15)21-11/h3,6,8-9,11,15,17-18H,2,4H2,1H3,(H,13,19,22)/t6-,8-,9-,11-/s3
InChIKeyHLZXTFWTDIBXDF-SOMIAQKHNA-N
SMILESOC[C@H]1O[C@@H](N2C=C(CC(OC)=O)C(=O)NC2=S)[C@H](O)[C@@H]1O |&1:2,4,18,20,r|
應用領域
用途一
5-(Methoxycarbonylmethyl)-2-thiouridine can be used as analyte in biological study for attomole quantification and global profile of RNA modifications in study of epitranscriptome of human neural stem cells. It can also be used to biological computational studies to provide insights into effects of modified ribonucleotides and Mg2+ on structures and stabilities of tRNAs. A trace nucleoside, isolated from yeast transfer RNA. A nucleoside in the anticodon at the wobble position of some Saccharomyces cerevisiae bacteria.