2049025-67-2
中文名稱
AB005-11雜質(zhì)
英文名稱
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
CAS
2049025-67-2
分子式
C40H57N5O7
分子量
719.91
MOL 文件
2049025-67-2.mol
更新日期
2026/07/14 17:42:01
2049025-67-2 結(jié)構(gòu)式
基本信息
中文別名
卡非佐米雜質(zhì)13卡非佐米雜質(zhì)39
AB005-11雜質(zhì)
英文別名
Kyprolis Impurity 39(R,S)-Epoxy Leucine Carfilzomib
(S)-4-Methyl-N-((S)-1-(((R)-4-Methyl-1-((S)-2-Methyloxiran-2-yl)-1-oxopentan-2-yl)aMino)-1-oxo-3-phenylpropan-2-yl)-2-((S)-2-(2-MorpholinoacetaMido)-4-phenylbutanaMido)pentanaMide
物理化學(xué)性質(zhì)
沸點975.6±65.0 °C(Predicted)
密度1.161±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)13.17±0.46(Predicted)
應(yīng)用領(lǐng)域
用途一
(αS)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1R)-3-methyl-1-[[(2S)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide is an impurity of Carfilzomib (C183460), which is a second-generation proteasome inhibitor that is used as a treatment in relapsed and refractory multiple myeloma.