2055047-18-0
中文名稱
Azido-PEG3-Val-Cit-PAB-PNP
英文名稱
Azido-PEG3-Val-Cit-PAB-PNP
CAS
2055047-18-0
分子式
C34H47N9O12
分子量
773.8
MOL 文件
2055047-18-0.mol
更新日期
2025/04/20 17:58:05
2055047-18-0 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
溶解度Soluble in DMSO, DMF
形態(tài)Solid
顏色White to light yellow
InChIKeyHLBCDJANEWKOSX-XIKWSGLJNA-N
SMILES[C@@H](CCCNC(=O)N)(NC(=O)[C@H](C(C)C)NC(=O)CCOCCOCCOCCN=[N+]=[N-])C(=O)NC1C=CC(COC(=O)OC2C=CC(N(=O)=O)=CC=2)=CC=1 |&1:0,11,r|
Azido-PEG3-Val-Cit-PAB-PNP價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-140150 | Azido-PEG3-Val-Cit-PAB-PNP | 2055047-18-0 | 5 mg | 1025元 |
| 2026/06/05 | HY-140150 | Azido-PEG3-Val-Cit-PAB-PNP | 2055047-18-0 | 10 mg | 1640元 |
| 2026/06/05 | HY-140150 | Azido-PEG3-Val-Cit-PAB-PNP | 2055047-18-0 | 25 mg | 3280元 |
常見(jiàn)問(wèn)題列表
生物活性
Azido-PEG3-Val-Cit-PAB-PNP 是一種可降解 (cleavable) 的含 3 個(gè)單元 PEG 的 ADC linker，可用于合成抗體偶聯(lián)藥物 (ADC)。Azido-PEG3-Val-Cit-PAB-PNP 還是一種 PROTAC linker，屬于 PEG 類，可用于合成 PROTAC 分子。靶點(diǎn)
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PEGs
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Cleavable
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體外研究
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.