2055048-45-6
中文名稱
活性單砜-八聚乙二醇-羧酸
英文名稱
Active-Mono-Sulfone-PEG8-acid
CAS
2055048-45-6
分子式
C37H53NO14S
分子量
767.88
MOL 文件
2055048-45-6.mol
更新日期
2026/07/14 17:33:03
2055048-45-6 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
沸點(diǎn)903.1±65.0 °C(Predicted)
密度1.210±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)4.28±0.10(Predicted)
應(yīng)用領(lǐng)域
用途一
Active-Mono-Sulfone-PEG8-acid is a PEG linker with a sulfone and acid end group. The sulfone group can be conjugated with thiol groups of proteins. The terminal carboxylic acid can react with primary amines in the presence of activators such as EDC and HATU to from stable amide bonds. The hydrophilic PEG chain increases the water solubility of the compound in aqueous media.