2062663-62-9
中文名稱
AMINOOXY-PEG4-CH2CO2TBU
英文名稱
Aminooxy-PEG4-CH2CO2tBu
CAS
2062663-62-9
分子式
C14H29NO7
分子量
323.38
MOL 文件
2062663-62-9.mol
更新日期
2023/02/20 14:06:15
2062663-62-9 結(jié)構(gòu)式
基本信息
中文別名
氨基-四聚乙二醇 -TUB保護(hù)羧基 英文別名
Aminooxy-PEG4-CH2-BocAminooxy-PEG5-CH2CO2tBu
Aminooxy-PEG4-CH2CO2tBu
所屬類別
催化劑及助劑：聚合物物理化學(xué)性質(zhì)
沸點(diǎn)418.5±40.0 °C(Predicted)
密度1.082±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)4.21±0.70(Predicted)
InChIInChI=1S/C14H29NO7/c1-14(2,3)22-13(16)12-20-9-8-18-5-4-17-6-7-19-10-11-21-15/h4-12,15H2,1-3H3
InChIKeyYIWYEQPSYTYCHV-UHFFFAOYSA-N
SMILESC(OC(C)(C)C)(=O)COCCOCCOCCOCCON
應(yīng)用領(lǐng)域
用途一
Aminooxy-PEG4-CH2CO2tBu is a PEG derivative containing an aminooxy group and a t-butyl ester group. The hydrophilic PEG spacer increases solubility in aqueous media. The aminooxy group can be used in bioconjugation. It reacts with an aldehyde to form an oxime bond. If a reductant is used, it will form a hydroxylamine linkage. The t-butyl protected carboxyl group can be hydrolyzed to form a free acid. Aminooxy compounds are very reactive and sensitive; they cannot be stored for long term. Immediate use (within 1 week) is highly recommended.