20633-84-5
中文名稱
忍冬苷
英文名稱
LONICERIN
CAS
20633-84-5
分子式
C27H30O15
分子量
594.52
MOL 文件
20633-84-5.mol
更新日期
2026/05/19 12:34:50
20633-84-5 結(jié)構(gòu)式
基本信息
中文別名
忍冬苷 英文別名
Luteolin-7-O-rhamnosideLuteoline-7-rhamnoglucoside
Luteolin 7-O-Rutinoside (Scolymoside)
Luteolin 7-rutinoside >=95% (LC/MS-ELSD)
所屬類別
天然產(chǎn)物：生物堿物理化學(xué)性質(zhì)
熔點(diǎn)192-196 °C
沸點(diǎn)954.0±65.0 °C(Predicted)
密度1.76±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C
溶解度DMSO: soluble
酸度系數(shù)(pKa)6.10±0.40(Predicted)
形態(tài)A solid
顏色Light yellow to yellow
主要應(yīng)用metabolomics
vitamins, nutraceuticals, and natural products
vitamins, nutraceuticals, and natural products
InChIKeyMGYBYJXAXUBTQF-PFQQTDEKNA-N
SMILESC[C@@H]1O[C@@H](OC[C@H]2O[C@@H](Oc3cc(O)c4C(=O)C=C(Oc4c3)c5ccc(O)c(O)c5)[C@H](O)[C@@H](O)[C@@H]2O)[C@H](O)[C@H](O)[C@H]1O
常見問題列表
生物活性
Luteolin-7-rutinoside 具有抗關(guān)節(jié)炎和抗真菌的雙重作用，可用于研究白色念珠菌感染引起的真菌關(guān)節(jié)炎。體外研究
At a dose of 10 μg Luteolin-7-rutinoside (lonicerin)/mL, there is an approximately 47% decrease of the proliferation as compared to proliferation of Luteolin-7-rutinoside treated (control) T cells (p<0.05). Luteolin-7-rutinoside at 40 μg/mL dose give almost the same rate of T cell proliferation as does 20 μg/mL dose of Luteolin-7-rutinoside. The suppressive activity is dose dependent. Luteolin-7-rutinoside treatment swifts Th1-Th2 balance away from Th1-toward Th2-type responses. Luteolin-7-rutinoside inhibits nitric oxide (NO) production from macrophages.