206367-33-1
中文名稱
PBD-1
CAS
206367-33-1
常見(jiàn)問(wèn)題列表
生物活性
pBD-1 是一種來(lái)源于豬組織的內(nèi)源性組成型表達(dá)的抗菌肽 (AMP)，尤其在豬黏膜上皮部位表達(dá)。pBD-1 具有抗菌作用，并且有助于豬黏膜和系統(tǒng)宿主防御。靶點(diǎn)
IC50: bacterial
體外研究
In a northern blot analysis, pBD-1 mRNA only expresses in ongue epithelial tissues from 4-5 week old pigs.In RT-PCR analysis, pBD-1 message throughout the epithelia of the respiratory (from nasal septum to lung) and gastrointestinal (from esophagus to rectum) tracts. In addition, it is detected in thymus, spleen, lymph node, brain, liver, kidney, urinary bladder, testis, skin, heart, muscle, bone marrow, alveolar macrophages, peripheral blood neutrophils and the umbilical cord. The only cells evaluated that does not express pBD-1 are peripheral blood mononuclear cells.