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20858-86-0

中文名稱 維生素B15
英文名稱 VITAMIN B15, PANGAMIC ACID
CAS 20858-86-0
分子式 C10H19NO8
分子量 281.26
MOL 文件 20858-86-0.mol
20858-86-0 結(jié)構(gòu)式 20858-86-0 結(jié)構(gòu)式

基本信息

英文別名
D-Gluconic acid, 6-ester with N,N-dimethylglycine

物理化學(xué)性質(zhì)

沸點571.7±50.0 °C(Predicted)
密度1.476±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)3.32±0.35(Predicted)

常見問題列表

生物活性
Vitamin B15 (Pangamic Acid) 是一種天然的,植物種子中廣泛存在的物質(zhì),可以用作刺激細(xì)胞呼吸的物質(zhì)。Vitamin B15 含有 D-葡萄糖基二甲基氨基乙酸。Vitamin B15 也是一種免疫校正劑。Vitamin B15 可用于多種疾病的研究。
體外研究

Unequivocal reports on identity and functions of Vitamin B15 (Pangamic Acid) in the literature make it impossible, however, to accurately assess either its chemical identity or its biological or medical functions. Indeed, the chemical identity of genuine Vitamin B15 (Pangamic Acid) has apparently never been ascertained or verifiably chemically identified as being the molecular weight 281-ester of DMG and gluconic acid claimed by Krebs and some Russian authors, and there is considerable doubt that such a stable substance exists with the straight chain sugar gluconic acid. Vitamin B15 (Pangamic Acid) is identified as a substance most likely containing both a sugar and a dimethylamine group.

體內(nèi)研究

Addition of Vitamin B15 (Pangamic Acid) to the diet (Wistar rats; 2.5 mg/100 g of diet) increases the degree of fatty infiltration of the liver which is maintained at a stable level throughout the whole experiment, i.e. 12-18 months.
Vitamin B15 (Pangamic Acid) enriches in the rat diet reduced glutathione peroxidase (after one year) and also glutathione transferase (after 18 months) in the brains of the animals, thus impairing their antioxidative capacities.
Vitamin B15 (Pangamic Acid) treatment increase the cytochrome oxidase- and also succinate dehydrogenase-activity in certain rat tissues.

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