2102101-72-2
中文名稱
IPN60090 DIHYDROCHLORIDE
英文名稱
2-Pyridineacetamide, 4-[(3,3-difluorocyclobutyl)oxy]-N-[6-[(3R)-3-fluoro-4-[4-[(methylamino)carbonyl]-1H-1,2,3-triazol-1-yl]butyl]-3-pyridazinyl]-6-methyl-, hydrochloride (1:2)
CAS
2102101-72-2
分子式
C24H28ClF3N8O3
分子量
568.99
MOL 文件
2102101-72-2.mol
2102101-72-2 結(jié)構(gòu)式
基本信息
英文別名
IPN60090 (dihydrochloride)2-Pyridineacetamide, 4-[(3,3-difluorocyclobutyl)oxy]-N-[6-[(3R)-3-fluoro-4-[4-[(methylamino)carbonyl]-1H-1,2,3-triazol-1-yl]butyl]-3-pyridazinyl]-6-methyl-, hydrochloride (1:2)
應(yīng)用領(lǐng)域
用途一
IACS-6274, also known as IPN60090, is a potent, selective and orally active glutaminase inhibitor with potential antineoplastic and immunostimulating activities. IPN60090 selectively targets, binds to and inhibits human glutaminase, an enzyme that is essential for the conversion of the amino acid glutamine into glutamate.常見問(wèn)題列表
概述
IPN-60090 dihydrochloride 是一種具有口服活性和高選擇性的谷氨酰胺酶 1 GLS1 的抑制劑 (IC50=31 nM)，對(duì) GLS-2 無(wú)活性。IPN-60090 dihydrochloride 在體內(nèi)表現(xiàn)出優(yōu)良的物理化學(xué)和藥代動(dòng)力學(xué)特性。IPN-60090 dihydrochloride 可用于實(shí)體腫瘤的研究，如肺癌和卵巢癌。IPN60090 DIHYDROCHLORIDE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-103671A | IPN60090 dihydrochloride | 2102101-72-2 | 1 mg | 1300元 |
| 2026/06/05 | HY-103671A | IPN60090 dihydrochloride | 2102101-72-2 | 5mg | 3200元 |
| 2026/06/05 | HY-103671A | IPN60090 DIHYDROCHLORIDE IPN60090 dihydrochloride | 2102101-72-2 | 10 mM * 1 mLin DMSO | 4262元 |