2102348-87-6
中文名稱
化合物 PEAQX SODIUM
英文名稱
[[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium salt
CAS
2102348-87-6
分子式
C17H20BrN3NaO6P
分子量
496.23
MOL 文件
2102348-87-6.mol
2102348-87-6 結(jié)構(gòu)式
基本信息
中文別名
化合物 PEAQX SODIUM 英文別名
[[[(1S)-1-(4-Bromophenyl)ethyl]amino](1,2,3,4-tetrahydro-2,3-dioxo-5-quinoxalinyl)methyl] phosphonic acid tetrasodium salt應(yīng)用領(lǐng)域
用途一
PEAQX, also known as NVP-AAM077; is a competitive antagonist at the NMDA receptor. Although originally described as 100-fold selective for GluN1/GluN2A receptors vs. GluN1/GluN2B receptors, more detailed studies of the Ki of PEAQX revealed it only shows a 5 fold difference in affinity for GluN1/GluN2A vs. GluN1/GluN2B receptors. It is also a potent anticonvulsant in animal tests.