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216167-92-9

中文名稱 216167-92-9
英文名稱 CAMOBUCOL
CAS 216167-92-9
分子式 C33H50O4S2
分子量 574.88
MOL 文件 216167-92-9.mol
216167-92-9 結構式 216167-92-9 結構式

基本信息

中文別名
化合物 T14861
英文別名
CAMOBUCOL
AGIX 4207
Acetic acid,2-[4-[[1-[[3,5-bis(1,1-diMethylethyl)-4-hydroxyphenyl]thio]-1-Methylethyl]thio]-2,6-bis(1,1-diMethylethyl)phenoxy]-

物理化學性質

熔點164-165 °C
沸點622.6±55.0 °C(Predicted)
密度1.11±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(pKa)3.23±0.10(Predicted)
形態(tài)Solid
顏色White to yellow
216167-92-9價格(試劑級)
報價日期產品編號產品名稱CAS號包裝價格
2026/06/05HY-14916Camobucol216167-92-91 mg1818元
2026/06/05HY-14916216167-92-9
Camobucol
216167-92-95mg4000元
2026/06/05HY-14916Camobucol216167-92-910 mM * 1 mLin DMSO5059元

常見問題列表

生物活性
Camobucol (AGIX 4207) 是一種可口服的酚類抗氧化劑和抗炎劑,用于風濕病的研究。
體外研究

Camobucol exhibits potent antioxidant activity toward lipid peroxides in vitro and displays enhanced cellular uptake. Camobucol selectively inhibits tumor necrosis factor (TNF)-α-inducible levels of the redox-sensitive genes, vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1, with less inhibition of E-selectin, and no effect on intracellular adhesion molecule-1 expression in endothelial cells. In addition, Camobucol inhibits cytokine-induced levels of monocyte chemoattractant protein-1, interleukin (IL)-6, and IL-8 from endothelial cells and human fibroblast-like synoviocytes as well as lipopolysaccharide-induced release of TNF-α, IL-1β, and IL-6 from human peripheral blood mononuclear cells. Camobucol does not inhibit TNF-α-induced nuclear translocation of nuclear factor of the κ-enhancer in B cells (NF-κB), suggesting that the mechanism of action is independent of this redox-sensitive transcription factor.

"216167-92-9" 相關產品信息
3561-67-9 109-04-6 23288-49-5
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