2172819-72-4
中文名稱
4-(((S)-1-((2S,4R)-4-HYDROXY-2-((4-(4-METHYLTHIAZOL-5-YL)BENZYL)CARBAMOYL)PYRROLIDIN-1-YL)-3,3-DIMET
英文名稱
L-Prolinamide, N-(3-carboxy-1-oxopropyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
CAS
2172819-72-4
分子式
C26H34N4O6S
分子量
530.64
MOL 文件
2172819-72-4.mol
2172819-72-4 結構式
基本信息
中文別名
4-(((S)-1-((2S,4R)-4-HYDROXY-2-((4-(4-METHYLTHIAZOL-5-YL)BENZYL)CARBAMOYL)PYRROLIDIN-1-YL)-3,3-DIMET 英文別名
VH 032 amide-alkylC2-acid(S,R,S)-AHPC-amido-C2-acid
L-Prolinamide, N-(3-carboxy-1-oxopropyl)-3-methyl-L-valyl-4-hydroxy-N-[[4-(4-methyl-5-thiazolyl)phenyl]methyl]-, (4R)-
4-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-4-oxobutanoic acid
物理化學性質
沸點868.3±65.0 °C(Predicted)
密度1.306±0.06 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度methanol, ethyl acetate, DCM, THF, DMF, DMSO
酸度系數(shù)(pKa)4.70±0.10(Predicted)
形態(tài)Solid
顏色Off-white to light yellow
外觀beige powder
應用領域
用途一
(S,R,S)-AHPC-amido-C2-acid is a VHL ligand with a 2 carbon alkyl linker and terminal acid for PROTAC compounds.