2181665-31-4
英文名稱
GSK-2239633
(GSK2239633)
CAS
2181665-31-4
分子式
C21H19ClN4O5S2
分子量
506.98
MOL 文件
2181665-31-4.mol
2181665-31-4 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
GSK2239633 is a potent CC-chemokine receptor 4 antagonist with pIC50 of 7.9. The CC-chemokine receptor 4 (CCR4) is thought potentially to play a critical role in asthma pathogenesis due to its ability to recruit type 2 T-helper lymphocytes to the inflamed airways. Therefore, CCR4 provides an excellent target for anti-inflammatory therapy.