2219331-30-1
2219331-30-1 結(jié)構(gòu)式
物理化學(xué)性質(zhì)
密度1.21±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMF: 5 mg/mL; DMF:PBS (pH 7.2) (1:5): 0.16 mg/mL; DMSO: 20 mg/mL
酸度系數(shù)(pKa)11.43±0.10(Predicted)
形態(tài)結(jié)晶固體
應(yīng)用領(lǐng)域
用途一
BB-F-Yne is a cell-permeable derivative of the protein arginine diminase (PAD) inhibitor BB-Cl-amidine that contains an alkyne moiety for use in click chemistry reactions. BB-F-Yne inhibits PAD1-4 and has been used for labeling PADs in cell-free and cell-based assays, followed by click reactions with azide-modified TAMRA or biotin reporters.