2235382-05-3
中文名稱
HDAC6 degrader 9c
英文名稱
HDAC6 degrader 9c
CAS
2235382-05-3
分子式
C37H45N9O10
分子量
775.81
MOL 文件
2235382-05-3.mol
2235382-05-3 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
HDAC6 degrader 9c, also known as dHDAC6 9c, is a bifunctional molecule that selectively degrades HDAC6 by conjugating a non-selective HDAC inhibitor to a thalidomide-type E3 ligase ligand. This process causes degradation of HDAC6 in a dose dependent manner and upregulation of acetylated α-tubulin.