2407529-33-1
中文名稱
Estrogen receptor antagonist 1
英文名稱
Estrogen receptor antagonist 1
CAS
2407529-33-1
分子式
C31H37F5N4O7
分子量
672.65
MOL 文件
2407529-33-1.mol
更新日期
2026/05/28 12:24:06
2407529-33-1 結(jié)構(gòu)式
應(yīng)用領(lǐng)域
用途一
Giredestrant, also known as GDC-9545 and RG6171, is a SERD. GDC-9545 is an orally available selective estrogen receptor degrader/downregulator (SERD), with potential antineoplastic activity. Upon oral administration, SERD GDC-9545 specifically targets and binds to the estrogen receptor (ER) and induces a conformational change that promotes ER degradation.