2663837-73-6
英文名稱
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, 1-[[[(1S)-1-formyl-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]amino]carbonyl]hexahydro-, phenylmethyl ester, (3aR,6aS)-
CAS
2663837-73-6
分子式
C23H29N3O5
分子量
427.49
MOL 文件
2663837-73-6.mol
2663837-73-6 結(jié)構(gòu)式
基本信息
英文別名
Cyclopenta[c]pyrrole-2(1H)-carboxylic acid, 1-[[[(1S)-1-formyl-2-[(3S)-2-oxo-3-pyrrolidinyl]ethyl]amino]carbonyl]hexahydro-, phenylmethyl ester, (3aR,6aS)-應(yīng)用領(lǐng)域
用途一
UAWJ9-36-1 is a SARS-CoV-2 Protease inhibitor (IC50 = 51 nM). UAWJ9-36-1 showed potent binding and enzymatic inhibition against the Mpro's from SARS-CoV-2, SARS-CoV, MERS-CoV, HCoV-OC43, HCoV-NL63, HCoV-229E, and HCoV-HKU1. UAWJ9-36-1 is a promising candidate to be further developed as a broad-spectrum coronavirus antiviral.