27653-67-4
中文名稱
TRIMETHOPRIM 3-OXIDE
英文名稱
Trimethoprim N-oxide 3
CAS
27653-67-4
分子式
C14H18N4O4
分子量
306.32
MOL 文件
27653-67-4.mol
更新日期
2025/06/11 16:41:57
27653-67-4 結(jié)構(gòu)式
基本信息
中文別名
甲氧芐氨嘧啶N-氧化物3 英文別名
Trimethoprim 3-oxideTrimethoprim 3-N-oxide
Trimethoprim N-oxide 3
Trimethoprim 3-oxide (Trimethoprim 3-N-oxide)
Trimethoprim 3-oxide (Synonyms: Trimethoprim 3-N-oxide)
2,4-Pyrimidinediamine, 5-[(3,4,5-trimethoxyphenyl)methyl]-, 3-oxide
物理化學(xué)性質(zhì)
沸點(diǎn)563.9±60.0 °C(Predicted)
密度1.36±0.1 g/cm3(Predicted)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度可溶于DMSO（少許）、甲醇（少許）
酸度系數(shù)(pKa)4.85±0.50(Predicted)
形態(tài)固體
顏色黃色到米色
TRIMETHOPRIM 3-OXIDE價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | HY-100645 | TRIMETHOPRIM 3-OXIDE Trimethoprim 3-oxide | 27653-67-4 | 1mg | 1300元 |
| 2025/12/22 | HY-100645 | TRIMETHOPRIM 3-OXIDE Trimethoprim 3-oxide | 27653-67-4 | 5 mg | 3900元 |
| 2024/08/19 | HY-100645 | TRIMETHOPRIM 3-OXIDE Trimethoprim 3-oxide | 27653-67-4 | 10 mg | 6200元 |
常見(jiàn)問(wèn)題列表
生物活性
Trimethoprim 3-oxide 為一種三甲氧芐二氨嘧啶的初級(jí)代謝物。體外研究
Trimethoprim 3-oxide is the primary metabolite of trimethoprim.
Trimethoprim 3-oxide (3-NO-TMP) is converted from trimethoprim by CYP1A1 and CYP1B1 with highest rates in human liver microsomes (HLMs). The CYP1A inhibitor α-Naphthoflavone inhibits Trimethoprim 3-oxide formation, however, other competitive P450 inhibitors has no obvious inhibition on the formation.