299-78-5
中文名稱
Allylisopropylacetamide
英文名稱
Allylisopropylacetamide
CAS
299-78-5
分子式
C8H15NO
分子量
141.21
MOL 文件
299-78-5.mol
299-78-5 結(jié)構(gòu)式
基本信息
中文別名
2-異丙基戊-4-烯酰胺 英文別名
AIAAllylisopropylacetamide
2-Isopropyl-4-pentenamide
2-isopropylpent-4-enamide
2-propan-2-ylpent-4-enamide
2-ALLYL-2-ISOPROPYL-ACETAMIDE
2-(1-Methylethyl)-4-pentenamide
4-Pentenamide, 2-(1-methylethyl)-
Allylisopropylacetamide(porphyria inducer)
物理化學(xué)性質(zhì)
熔點(diǎn)98-100 °C
沸點(diǎn)251.3±19.0 °C(Predicted)
密度0.898±0.06 g/cm3(Predicted)
酸度系數(shù)(pKa)16.57±0.50(Predicted)
安全數(shù)據(jù)
毒性An irreversible inhibitor of
cytochrome P450. It is first oxidized by the cytochrome to a
reactive intermediate that binds covalently to the heme moiety
of the cytochrome. The subsequent breakdown of the heme
gives rise to characteristic pigments. This was an early example
of a “suicide inhibitor.”