320725-47-1
中文名稱
EVIZON; MSI 1256F
英文名稱
SqualaMine lactate
CAS
320725-47-1
分子式
C37H71N3O8S
分子量
718.05
MOL 文件
320725-47-1.mol
320725-47-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T12996 英文別名
EvizonMSI 1256F
MSI-1256F, >95%
EVIZON
MSI 1256F
SqualaMine lactate
Squalamine lactate?, >95%
物理化學(xué)性質(zhì)
儲(chǔ)存條件-20°C儲(chǔ)存
溶解度DMSO : ≥ 36.66 mg/mL (51.06 mM)
形態(tài)Solid
顏色Light yellow to yellow
EVIZON; MSI 1256F價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-16467 | EVIZON; MSI 1256F Squalamine lactate | 320725-47-1 | 1mg | 4500元 |
| 2026/06/05 | HY-16467 | EVIZON; MSI 1256F Squalamine lactate | 320725-47-1 | 10 mM * 1 mL in DMSO | 13901元 |
| 2024/08/19 | HY-16467 | EVIZON; MSI 1256F Squalamine lactate | 320725-47-1 | 5mg | 8800元 |
常見問題列表
生物活性
Squalamine lactate 是一種從角鯊體內(nèi)分到的氨基甾醇，具有抗菌活性，同時(shí)可用于新生血管性年齡相關(guān)性黃斑變性的研究。體外研究
Squalamine lactate has a more generalized effect on the cellular signaling cascade that is common to both VEGF and other growth factors. Squalamine blocks the action of VEGF and integrin expression, thereby inhibiting angiogenesis, when bound to calmodulin.
體內(nèi)研究
Squalamine is ineffective when administered intravitreally and therefore requires intravenous dosing. However, systemic dosing has yielded promising results in rats as well as humans.