329187-86-2
中文名稱
2'-F-2'-ARA-BZ-DA 亞磷酰胺單體
英文名稱
2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
CAS
329187-86-2
分子式
C47H51FN7O7P
分子量
875.94
MOL 文件
329187-86-2.mol
更新日期
2026/07/02 16:45:39
329187-86-2 結(jié)構(gòu)式
基本信息
中文別名
2'-F-2'-ARA-BZ-DA 亞磷酰胺單體2'-F-2'-ARA-DA(BZ) 亞磷酰胺單體
英文別名
2'-F-2'-ara-Bz-dA Phosphoramidite2'-F-dA(Bz)-ANA-CE Phosphoramidite
2'-Fluoro-2'-deoxy-ara-A-3'-phosphoramidite
N6-Bz-5'-O-DMTr-2'-fluoro-2'-deoxyarabinoadenosine-3'-CED-phosphoramidite
5'-O-DMT-2'-Fluoro-N6-Benzoyl-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite
5'-O-DMT-N6-Benzoyl-2'-fluoro-2'-arabinofuranosyl-2'-deoxyadenosine 3'-CE phosphoramidite
N6-Benzoyl-5'-O-(4,4'-dimethoxytrityl)-2'-fluoro-2'-deoxyarabino adenosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite
Benzamide, N-[9-[5-O-[bis(4-methoxyphenyl)phenylmethyl]-3-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2-deoxy-2-fluoro-β-D-arabinofuranosyl]-9H-purin-6-yl]-
N6-Benzoyl-5’-O-(4,4’-dimethoxytrityl)-2’-fluoro-2’-deoxyarabinoadenosine-3’-O-[(2-cyanoethyl)-(N,N-diisopropyl)]phosphoramidite, 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite
所屬類別
生物：磷酸酶抑制劑物理化學(xué)性質(zhì)
溶解度DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
酸度系數(shù)(pKa)8.80±0.10(Predicted)
形態(tài)Solid
顏色White to off-white
InChIInChI=1/C47H51FN7O7P/c1-31(2)55(32(3)4)63(60-27-13-26-49)62-42-39(61-46(40(42)48)54-30-52-41-43(50-29-51-44(41)54)53-45(56)33-14-9-7-10-15-33)28-59-47(34-16-11-8-12-17-34,35-18-22-37(57-5)23-19-35)36-20-24-38(58-6)25-21-36/h7-12,14-25,29-32,39-40,42,46H,13,27-28H2,1-6H3,(H,50,51,53,56)/t39-,40+,42-,46-,63?/s3
InChIKeyVCCMVPDSLHFCBB-JGVLZJSQNA-N
SMILESC(C1C=CC=CC=1)(C1C=CC(OC)=CC=1)(C1C=CC(OC)=CC=1)OC[C@H]1O[C@@H](N2C=NC3=C(N=CN=C23)NC(C2C=CC=CC=2)=O)[C@@H](F)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C |&1:25,27,46,48,r|
常見(jiàn)問(wèn)題列表
概述
2'-F-2'-ARA-BZ-DA 亞磷酰胺單體 是一種腺嘌呤核苷類似物。腺苷類似物大多可作為平滑肌血管擴(kuò)張劑，也被證明能夠抑制癌癥進(jìn)展。它的熱門產(chǎn)品有 Adenosine phosphate，Acadesine (HY-13417)，Clofarabine (HY-A0005)，F(xiàn)ludarabine phosphate (HY-B0028) 和 Vidarabine (HY-B0277)。2'-F-2'-ARA-BZ-DA 亞磷酰胺單體價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-154409 | 2'-F-2'-ARA-BZ-DA 亞磷酰胺單體 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite | 329187-86-2 | 5 mg | 320元 |
| 2026/06/05 | HY-154409 | 2'-F-2'-ARA-BZ-DA 亞磷酰胺單體 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite | 329187-86-2 | 10 mg | 600元 |
| 2026/06/05 | HY-154409 | 2'-F-2'-ARA-BZ-DA 亞磷酰胺單體 2’-Fluoro-2’-deoxy-ara-A(Bz)-3’-phosphoramidite | 329187-86-2 | 25 mg | 1400元 |