3684-73-9
中文名稱
化合物 ETHIONAMIDE HCL
英文名稱
2-ethylthioisonicotinamide monohydrochloride
CAS
3684-73-9
分子式
C8H11ClN2S
分子量
202.704
MOL 文件
3684-73-9.mol
3684-73-9 結(jié)構(gòu)式
基本信息
中文別名
化合物 ETHIONAMIDE HCL 英文別名
Ethionamide HClEinecs 222-972-7
Ethionamide hydrochloride
2-ethylthioisonicotinamide monohydrochloride
應(yīng)用領(lǐng)域
用途一
Ethionamide HCl is the salt form of Ethionamide, a second-line antitubercular agent that inhibits mycolic acid synthesis. Ethionamide is a nicotinamide derivative, with antibacterial activity, used to treat tuberculosis. Although the exact mechanism of action of ethionamide is unknown, it may inhibit the synthesis of mycolic acid, a saturated fatty acid found in the bacterial cell wall, thereby inhibiting bacterial cell wall synthesis. This eventually leads to bacterial cell wall disruption and cell lysis. Ethionamide may be bacteriostatic or bactericidal in action, depending on the concentration of the drug at the site of infection and the susceptibility of the organism involved. It binds with NAD+ to form an adduct.