371135-20-5
中文名稱
化合物 T28868
英文名稱
ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate
CAS
371135-20-5
分子式
C27H23N3O4
分子量
453.489
MOL 文件
371135-20-5.mol
371135-20-5 結(jié)構(gòu)式
基本信息
中文別名
化合物 T28868 英文別名
ethyl {2-methyl-3-[2-(naphtho[2,1-b]furan-2-ylcarbonyl)carbohydrazonoyl]-1H-indol-1-yl}acetate應(yīng)用領(lǐng)域
用途一
STK899704 is a novel tubulin inhibitor, preventing the polymerization of purified tubulin in vitro and depolymerizing microtubule in cultured cells leading to mitotic arrest, associated with increased Cdc25C phosphorylation and the accumulation of both cyclin B1 and polo-like kinase 1 (Plk1), and apoptosis.