376364-36-2
中文名稱
抗菌肽CRAMP
英文名稱
CATHELICIDIN RELATED ANTIMICROBIAL PEPTIDE (MOUSE)
CAS
376364-36-2
分子式
C178H302N50O46
更新日期
2026/06/01 19:17:32
基本信息
中文別名
GQ-34抗菌肽CRAMP
英文別名
CRAMPCLP (MOUSE)
CRAMP (MOUSE)
CATHELICIDIN RELATED ANTIMICROBIAL PEPTIDE (MOUSE)
H-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-Lys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH
H-GLY-LEU-LEU-ARG-LYS-GLY-GLY-GLU-LYS-ILE-GLY-GLU-LYS-LEU-LYS-LYS-ILE-GLY-GLN-LYS-ILE-LYS-ASN-PHE-PHE-GLN-LYS-LEU-VAL-PRO-GLN-PRO-GLU-GLN-OH (MOUSE)
CRAMP (mouse) trifluoroacetate salt H-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-Lys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH trifluoroacetate salt
物理化學(xué)性質(zhì)
形態(tài)Solid
顏色White to off-white
序列H-Gly-Leu-Leu-Arg-Lys-Gly-Gly-Glu-Lys-Ile-Gly-Glu-Lys-Leu-Lys-Lys-Ile-Gly-Gln-Lys-Ile-Lys-Asn-Phe-Phe-Gln-Lys-Leu-Val-Pro-Gln-Pro-Glu-Gln-OH
應(yīng)用領(lǐng)域
多肽
CRAMP (mouse)是一種在小鼠體內(nèi)發(fā)現(xiàn)的抗菌肽，是一條由34個(gè)氨基酸組成的多肽。CRAMP (mouse)在動(dòng)物模型直言中，可以通過抑制膠原的表達(dá)與積累，從而緩解腸炎動(dòng)物的腸道纖維化病變。可以說CRAMP (mouse)是一種小鼠體內(nèi)對(duì)應(yīng)于人體內(nèi)LL-37的抗菌肽。參考質(zhì)量標(biāo)準(zhǔn)
外觀:白色粉末純度(HPLC) ≥98.0%
醋酸根含量≤12.0%
水分含量≤8.0%
肽含量≥80.0%
內(nèi)毒素≤50EU/mg
氨基酸組成分析≤±10%