379247-14-0
中文名稱
化合物 T26840
英文名稱
8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]-
CAS
379247-14-0
分子式
C20H21N5O
分子量
347.41
MOL 文件
379247-14-0.mol
379247-14-0 結(jié)構(gòu)式
基本信息
中文別名
化合物 T26840 英文別名
BMH7BMH-7
BMH 7
8H-Phthalazino[1,2-b]quinazolin-8-one, 5-[[3-(dimethylamino)propyl]amino]-
物理化學(xué)性質(zhì)
沸點(diǎn)532.9±52.0 °C(Predicted)
密度1.27±0.1 g/cm3(Predicted)
酸度系數(shù)(pKa)9.43±0.28(Predicted)
應(yīng)用領(lǐng)域
用途一
BMH-7 is a p53 activator with potent antitumor activity. It regulates the p53 signaling pathway in bladder cancer cells. BMH-7 also induces apoptosis, changes cell size, and leads to cell death. BMH-7 is derived from quinazolinone, a small molecule that is able to activate the p53 tumor suppressor pathway.