37988-18-4
37988-18-4 結(jié)構(gòu)式
基本信息
N,N',N''-三(2-羥基乙基)-1,3,5-苯三甲酰胺
LM 22A4
LM 22A4
LM 22A-4
N,N',N''-Tris(beta-hydroxyethyl)trimesamide
N1,N3,N5-Tris(2-hydroxyethyl)-1,3,5-benzenetricarboxamide
1,3,5-Benzenetricarboxamide, N1,N3,N5-tris(2-hydroxyethyl)-
1-N,3-N,5-N-TRIS(2-HYDROXYETHYL)BENZENE-1,3,5-TRICARBOXAMIDE
物理化學(xué)性質(zhì)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/07/06 | S0827 | LM 22A4 LM22A-4 | 37988-18-4 | 5mg | 1170.58元 |
| 2026/07/06 | S0827 | LM 22A4 LM22A-4 | 37988-18-4 | 25mg | 3290.43元 |
| 2026/06/05 | HY-100673 | LM22A-4 | 37988-18-4 | 1 mg | 234元 |
常見問題列表
| Target | Value |
|
TrkB
() |
LM22A-4 significantly up-regulates OPN and ALPase mRNA expression in a dose-dependent manner and OC mRNA level is significantly increased by 5 μM of LM22A-4. LM22A-4 significantly increases OPN, ALPase and OC mRNA expression in a time-dependent manner. LM22A-4 stimulated OPN and OC mRNA expression in HCEM cells cultured with mineralizing media.
LM22A-4 (10 mg/kg, i.p.) significantly reduces the degree of tissue injury and apoptosis (TUNEL staining and caspase-3 and Bcl-2 expression) compared with vehicle treated group. LM22A-4 also significantly ameliorates the recovery of limb function. LM22A-4 (10 mg/kg) treatment results in a significant increase in neuron number. LM22A-4 administration (10 mg/kg) significantly improves the neurological scores compared with those of the solvent-treated animals.