39740-30-2
中文名稱
L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
英文名稱
L-DOPA Ethyl Ester Hydrochloride
CAS
39740-30-2
分子式
C11H16ClNO4
分子量
261.7
MOL 文件
39740-30-2.mol
39740-30-2 結(jié)構(gòu)式
基本信息
中文別名
左旋多巴乙酯鹽酸鹽L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽
英文別名
Etilevodopa hydrochlorideO-Ethyl-DOPA Hydrochloride
L-DOPA Ethyl Ester Hydrochloride
Levodopa Ethyl Ester Hydrochloride
3-Hydroxy-L-tyrosine Ethyl Ester Hydrochloride
3-hydroxy- L-Tyrosine ethyl ester, hydrochloride (1:1)
3,4-Dihydroxy-L-phenylalanine Ethyl Ester Hydrochloride
物理化學(xué)性質(zhì)
熔點(diǎn)51-54°C
儲(chǔ)存條件Hygroscopic, Refrigerator, Under Inert Atmosphere
溶解度Methanol, Water
形態(tài)Solid
顏色Off-White
水溶解性Water: 125 mg/mL (477.65 mM)
穩(wěn)定性Hygroscopic
L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/12/22 | HY-116016A | L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽 Etilevodopa hydrochloride | 39740-30-2 | 5mg | 350元 |
| 2025/12/22 | HY-116016A | L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽 Etilevodopa hydrochloride | 39740-30-2 | 10mg | 600元 |
| 2025/12/22 | HY-116016A | L-3,4-二羥基苯丙氨酸乙酯鹽酸鹽 Etilevodopa hydrochloride | 39740-30-2 | 25 mg | 1250元 |
常見問題列表
生物活性
Etilevodopa hydrochloride (L-Dopa ethyl ester hydrochloride) 是 Levodopa 的前藥，在胃腸道中被非特異性酯酶快速水解為 Levodopa 和乙醇。Etilevodopa 用于帕金森病 (PD)的相關(guān)研究。Levodopa 是多巴胺的直接前體，有助于中樞神經(jīng)系統(tǒng)的滲透和傳遞多巴胺。體外研究
Etilevodopa (L-Dopa ethyl ester) hydrochloride passes unchanged through the stomach to the duodenum, where it is rapidly hydrolyzed by local esterases to Levodopa and ethanol, and is subsequently absorbed into the blood stream as Levodopa.
Compared with standard Levodopa, Etilevodopa hydrochloride has greater solubility in the stomach, faster passage to the small intestine, and a shortened time to maximum Levodopa concentration.