501121-34-2
501121-34-2 結(jié)構(gòu)式
基本信息
中文別名
阿伐他汀鈉鹽阿托伐他汀EP雜質(zhì)E
阿托伐他汀USP相關(guān)物質(zhì)E
英文別名
S,S-Atorvastatin3S,5S-Atorvastatin Sodium
Atorvastatin EP Impurity E
S,S-Atorvastatin Sodium Salt
(3S,5S)-Atorvastatin Sodium Salt
Atorvastatin USP Related CoMpound E
(bS,dS)-2-(4-Fluorophenyl)-b,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid
1H-Pyrrole-1-heptanoic acid, 2-(4-fluorophenyl)-β,δ-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-, (βS,δS)-
(S,dS)-2-(4-Fluorophenyl)-,d-dihydroxy-5-(1-methylethyl)-3-phenyl-4-[(phenylamino)carbonyl]-1H-pyrrole-1-heptanoic Acid Sodium
(βS,δS)-2-(4-Fluorophenyl)-β,δ-dihydroxy-5-(1-Methylethyl)-3-phenyl-4-[(phenylaMino)carbonyl]-1H-pyrrole-1-heptanoic Acid SodiuM
(3S,5S)-阿伐他汀鈉鹽價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-B0589C | (3S,5S)-阿伐他汀鈉鹽 (3S,5S)-Atorvastatin | 501121-34-2 | 5 mg | 2000元 |
| 2026/06/05 | HY-B0589C | (3S,5S)-阿伐他汀鈉鹽 (3S,5S)-Atorvastatin | 501121-34-2 | 10 mM * 1 mL in DMSO | 2458元 |
| 2026/06/05 | HY-B0589C | (3S,5S)-阿伐他汀鈉鹽 (3S,5S)-Atorvastatin | 501121-34-2 | 10 mg | 3000元 |
常見(jiàn)問(wèn)題列表
生物活性
(3S,5S)-Atorvastatin 是 Atorvastatin 的無(wú)活性對(duì)映異構(gòu)體。(3S,5S)-Atorvastatin 可以激活孕烷 X 受體 (PXR)。Atorvastatin 是一種具有口服活性的 HMG-CoA 還原酶抑制劑，具有有效降低血脂的能力。靶點(diǎn)
Pregnane X receptor (PXR)
體外研究
Atorvastatin and its inactive enantiomer (3S,5S)-Atorvastatin increases CYP2B and CYP3A mRNA content with equal ability.
(3S,5S)-Atorvastatin in 100 μM concentrations induces luciferase activity with an EC
50
of 12.4 μM.
Addition of (3S,5S)-Atorvastatin to the 2-formylphenylboronic
acid (FPBA)/l-tryptophanol mixture induces an intensity enhancement of l-tryptophanol florescence.