5092-09-1
中文名稱
柴胡皂苷元A
英文名稱
saikogenin A
CAS
5092-09-1
分子式
C30H48O4
分子量
472.7
MOL 文件
5092-09-1.mol
更新日期
2026/02/25 10:15:29
5092-09-1 結(jié)構(gòu)式
基本信息
中文別名
柴胡皂苷元A 標準品 英文別名
Clinopodiside A1Oleana-11,13(18)-diene-3,16,23,28-tetrol, (3β,4α,16β)-
所屬類別
分析化學(xué)：藥典標準品和雜質(zhì)標準品物理化學(xué)性質(zhì)
熔點287-293 °C
沸點607.4±55.0 °C(Predicted)
密度1.16±0.1 g/cm3(Predicted)
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
酸度系數(shù)(pKa)14.47±0.70(Predicted)
形態(tài)Solid
顏色White to off-white
柴胡皂苷元A價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-N6584 | 柴胡皂苷元A Saikogenin A | 5092-09-1 | 1 mg | 2500元 |
| 2026/06/05 | HY-N6584 | 柴胡皂苷元A Saikogenin A | 5092-09-1 | 5 mg | 6000元 |
常見問題列表
生物活性
Saikogenin A 可從中藥柴胡中提取，是一種二肽基肽酶 IV (DPP-IV) 抑制劑。靶點
DPP-IV
體外研究
Saikogenin A has certain inhibitory effect on the enzyme DPP-IV. At a concentration of 20 μg/mL DPP-IV inhibition is 47.6%. DPP-IV is a non-classical serine aminopeptidase from its amino terminus of polypeptides and proteins (N-terminus) removing Xaa-Pro dipeptide.
體內(nèi)研究
Saikogenin A, an anti-inflammatory drug, is present in the crude extract of a Chinese herbal plant called Tsai-Fu. Saikogenin A is less effective in adrenalectomized rats than in normal rats in reducing the carrageenin-induced edema. The anti-inflammatory action of Saikogenin A are due to an increase in corticosterone caused by the release of arenocorticotropic hormone (ACTH) and a direct effect on the process of inflammation.