5168-36-5
5168-36-5 結(jié)構(gòu)式
基本信息
Oh-5-du
5-HYDROXY-2'-DEOXYURIDINE
2'-Deoxy-5-hydroxyuridine
Uridine, 2'-deoxy-5-hydroxy-
2'-DEOXY-5-HYDROXY-D-URIDINE
物理化學(xué)性質(zhì)
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱(chēng) | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-130801 | 5-HYDROXY-2'-DEOXYURIDINE 5-Hydroxy-2'-deoxyuridine | 5168-36-5 | 1mg | 394元 |
| 2026/06/05 | HY-130801 | 5-Hydroxy-2'-deoxyuridine | 5168-36-5 | 5 mg | 900元 |
| 2026/06/05 | HY-130801 | 5-HYDROXY-2'-DEOXYURIDINE 5-Hydroxy-2'-deoxyuridine | 5168-36-5 | 10 mM * 1 mLin DMSO | 990元 |
常見(jiàn)問(wèn)題列表
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Human Endogenous Metabolite
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To study the specificity of nucleotide incorporation opposite 5-hydroxypyrimidines in template DNA, 18- and 45-member oligodeoxyribonucleotides, containing an internal 2'-deoxy-5-hydroxyuridine (5-OHdU) in two different sequence contexts, were used. Translesion synthesis past 2'-deoxy-5-hydroxyuridine (5-OHdU) in both oligonucleotides occurred, but pauses both opposite, and one nucleotide prior to, the modified base in the template is observed. The specificity of nucleotide incorporation opposite 2'-deoxy-5-hydroxyuridine (5-OHdU) in the template is sequence context dependent. In one sequence context, dA is the principal nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). However in a second sequence context, dC is the predominant base incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU). In that same sequence context, dC is also the predominant nucleotide incorporated opposite 2'-deoxy-5-hydroxyuridine (5-OHdU).