53696-59-6
中文名稱
8-疊氮酰苷-5'-三磷酸鈉
英文名稱
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT
CAS
53696-59-6
分子式
C10H15N8O13P3
分子量
548.19
MOL 文件
53696-59-6.mol
53696-59-6 結(jié)構(gòu)式
基本信息
中文別名
8-疊氮酰苷-5'-三磷酸鈉 英文別名
8-N3-ATP SODIUM SALT8-azidoadenosine5’-triphosphate
8-azido-ATP - 10mM aqueous solution
8-azidoadenosine5’-triphosphatesodium
8-Azido-D-adenosine5'-triphosphatesodiumsalt
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT
8-AZIDOADENOSINE-5'-O-TRIPHOSPHATE SODIUM SALT
Adenosine 5'-(tetrahydrogen triphosphate), 8-azido-
8-AZIDOADENOSINE 5'-TRIPHOSPHATE, SODIUM SALT USP/EP/BP
8-azidoadenosine-5’-o-triphosphate(8-n3-atp),sodiumsalt
所屬類別
生物化工：核苷中間體常見(jiàn)問(wèn)題列表
生物活性
8-Azido-ATP 是一個(gè)光解性的核苷酸類似物，用于鑒定蛋白，如依賴于 DNA 的 RNA 聚合酶。體外研究
8-Azido-ATP can be used to identify the viral RNA polymerase on the basis of the ability of the analog to inhibit transcription activity associated with rotavirus particles on exposure to UV light.
8-Azido-ATP (azido-ATP) decreases viral transcription in a dose-dependent manner.
8-Azido-ATP blocks Kir6.2ΔC26 currents rather less potently than ATP, half-maximal inhibition (Ki) occurring at 2.8 ± 0.4 mM (n = 6) compared with 172 ± 7 mM for ATP (n = 6). The Hill coefficients were 0.9 ± 0.2 for 8-azido-ATP and 1.3 ± 0.1 for ATP.