554435-83-5
中文名稱
地拉羅斯鐵螯合物
英文名稱
Exjade Fe3+ chelate
CAS
554435-83-5
分子式
C21H12FeN3O4
分子量
426.19
MOL 文件
554435-83-5.mol
更新日期
2025/02/06 13:22:41
554435-83-5 結構式
基本信息
中文別名
地拉羅斯鐵螯合物 英文別名
Exjade Fe3+ chelateDeferasirox (Fe3+ chelate)
Deferasirox Fe3(addition) chelate
[4-[3,5-Bis[2-hydroxy)phenyl]-1H-1,2,4-triazol-1-yl]benzoato)]iron
所屬類別
生物化工：激動劑抑制劑物理化學性質
儲存條件-20°C儲存
溶解度溶于二甲基亞砜
形態(tài)粉末
顏色Light brown to black
InChIInChI=1S/C21H15N3O4.Fe/c25-17-7-3-1-5-15(17)19-22-20(16-6-2-4-8-18(16)26)24(23-19)14-11-9-13(10-12-14)21(27)28;/h1-12,25-26H,(H,27,28);/q;+3/p-3
InChIKeyABQALTGEPFNCIY-UHFFFAOYSA-K
SMILESC(C1C=CC(N2N=C3C4=CC=CC=C4[O-][Fe+3]4[O-]C5=CC=CC=C5C2=N34)=CC=1)(=O)[O-]
地拉羅斯鐵螯合物價格(試劑級)
| 報價日期 | 產(chǎn)品編號 | 產(chǎn)品名稱 | CAS號 | 包裝 | 價格 |
| 2026/06/05 | HY-16564 | 地拉羅斯鐵螯合物 Deferasirox (Fe3+ chelate) | 554435-83-5 | 5mg | 990元 |
| 2026/06/05 | HY-16564 | 地拉羅斯鐵螯合物 Deferasirox (Fe3+ chelate) | 554435-83-5 | 10mM * 1mLin DMSO | 1089元 |
| 2026/06/05 | HY-16564 | 地拉羅斯鐵螯合物 Deferasirox (Fe3+ chelate) | 554435-83-5 | 10mg | 1485元 |
常見問題列表
生物活性
Deferasirox Fe3+ chelate 是具有口活性的，可用于鐵離子過量的螯合劑。體外研究
Deferasirox is the first oral medication approved in the USA for this purpose. The half-life of deferasirox is between 8 and 16 hours allowing once a day dosing. Two molecules of deferasirox are capable of binding to 1 atom of iron which are subsequently eliminated by fecal excretion. Its low molecular weight and high lipophilicity allows the drug to be taken orally unlike desferoxamine which has to be administered by IV route (intravenous infusion). Together with deferiprone, deferasirox seems to be capable of removing iron from cells (cardiac myocytes and hepatocytes) as well as removing iron from the blood.