5673-36-9
中文名稱
二氫異海松酸
英文名稱
Isopimaric acid, delta7-dihydro-
CAS
5673-36-9
分子式
C20H32O2
分子量
304.47
MOL 文件
5673-36-9.mol
更新日期
2026/05/27 14:55:52
5673-36-9 結構式
基本信息
中文別名
二氫異海松酸 英文別名
DihydroisopimaricDihydroisopimaric Acid
Isopimaric acid, delta7-dihydro-
(1S,4aR,4bS,7S)-7-ethyl-1,4a,7-trimethyl-3,4,4b,5,6,8,10,10a-octahydro-2H-phenanthrene-1-carboxylic acid
1-Phenanthrenecarboxylic acid, 7-ethyl-1,2,3,4,4a,4b,5,6,7,8,10,10a-dodecahydro-1,4a,7-trimethyl-, (1R,4aR,4bS,7S,10aR)-
常見問題列表
生物活性
Dihydroisopimaric acid在全細胞電壓鉗位下，能夠激活 BK 通道 alphabeta1。體外研究
Effects of these compounds (10 microM) on the membrane potential of HEKBKalphabeta1 were monitored by use of DiBAC(4)(3), a voltage-sensitive dye. Dihydroisopimaric acid induces substantial membrane hyperpolarization. Dihydroisopimaric acid (1-10 microM) activates BKalphabeta1 in the direct measurement of BKalphabeta1 opening under whole-cell voltage clamp.