579492-81-2
中文名稱
579492-81-2
英文名稱
BAX INHIBITING PEPTIDE V5 (BIP-V5)
CAS
579492-81-2
分子式
C27H50N6O6S
分子量
586.79
MOL 文件
579492-81-2.mol
更新日期
2026/07/23 09:59:40
579492-81-2 結(jié)構(gòu)式
基本信息
中文別名
BAX抑制肽V5 英文別名
Val-Pro-Met-Leu-LysVAL-PRO-MET-LEU-LYS
BIP-V5
BAX INHIBITOR PEPTIDE V5, >99%
Bax inhibitor peptide V5 (BIP-V5)
BAX INHIBITING PEPTIDE V5 (BIP-V5)
L-Lysine, L-valyl-L-prolyl-L-methionyl-L-leucyl-
VAL-PRO-MET-LEU-LYS
BIP-V5
BAX INHIBITING PEPTIDE V5
BAX Inhibiting Peptide V5 >=97% (HPLC), lyophilized powder
Bax inhibitor peptide V5,Val-Pro-Met-Leu-Lys, BIP-V5,BAX Inhibiting Peptide V5, >99%
物理化學(xué)性質(zhì)
沸點(diǎn)907.2±65.0 °C(Predicted)
密度1.185±0.06 g/cm3(Predicted)
儲(chǔ)存條件-20°C
溶解度≥29.35 mg/mL in DMSO; insoluble in EtOH; ≥91.4 mg/mL in H2O
酸度系數(shù)(pKa)3.31±0.10(Predicted)
形態(tài)lyophilized powder
顏色White to off-white
InChIKeyNHMUTADCTDDWPV-YFNVTMOMSA-N
SMILESS(CC[C@H](NC(=O)[C@H]1N(CCC1)C(=O)[C@@H](N)C(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)O)C
579492-81-2價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-P0081 | 579492-81-2 Bax inhibitor peptide V5 | 579492-81-2 | 5 mg | 950元 |
| 2026/06/05 | HY-P0081 | 579492-81-2 Bax inhibitor peptide V5 | 579492-81-2 | 10 mg | 1400元 |
| 2026/06/05 | HY-P0081 | 579492-81-2 Bax inhibitor peptide V5 | 579492-81-2 | 25 mg | 3000元 |
常見問題列表
生物活性
Bax inhibitor peptide V5 (BIP-V5) 是一種 Bax 誘導(dǎo)凋亡的抑制劑，主要用于癌癥研究。靶點(diǎn)
|
Bax
|
體外研究
Bax inhibitor peptide V5 (BIP-V5; 0-50 μM) reduces cell death in STF-cMyc cells but not in SW620 or NCI-H23 cells. BIPV5 does not result in any significant effect on cell cycle arrest at the G2/M phase. V5 treatment upregulates expression of anti-apoptotic proteins Bcl-2 and XIAP by more than 3- and 11-fold and downregulates expression of apoptosis-inducing proteins Bax, Bad, and nuclear factor-κB-p65 by 10, 30, and nearly 50%, respectively.
體內(nèi)研究
Bax inhibitor peptide V5 (BIP-V5; 100 μM) significantly improves islet function following isolation and improves islet graft function following transplantation in mice model.