591778-83-5
中文名稱
CP-610431
英文名稱
(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]-N,N-diethylpiperidine-3-carboxamide
CAS
591778-83-5
分子式
C30H37N3O2
分子量
471.634
MOL 文件
591778-83-5.mol
591778-83-5 結(jié)構(gòu)式
基本信息
英文別名
CP-610431(3R)-1-[1-(anthracene-9-carbonyl)piperidin-4-yl]-N,N-diethylpiperidine-3-carboxamide
應(yīng)用領(lǐng)域
用途一
CP-610431 is an isozyme-nonselective ACC inhibitor. CP-610431 inhibited ACC1 and ACC2 with IC50s of approximately 50 nm. Inhibition was reversible, uncompetitive with respect to ATP, and non-competitive with respect to bicarbonate, acetyl-CoA, and citrate, indicating interaction with the enzymatic carboxyl transfer reaction.