59943-31-6
中文名稱
DU 717
英文名稱
DU 717
CAS
59943-31-6
分子式
C12H15ClN4O2S
分子量
314.796
MOL 文件
59943-31-6.mol
更新日期
2023/03/17 20:03:07
59943-31-6 結(jié)構(gòu)式
基本信息
中文別名
化合物DU717化合物 T11109
英文別名
DU 7177-chloro-3-(4-methyl-1-piperazinyl)-2H-1,2,4-benzothiadiazine 1,1-dioxide
2H-1,2,4-Benzothiadiazine, 7-chloro-3-(4-methyl-1-piperazinyl)-, 1,1-dioxide
常見問題列表
生物活性
DU-717 是一種抗高血壓劑。體內(nèi)研究
A gas chromatographic method has been developed which enables accurate determination of a new antihypertensive agent, DU-717, in plasma. Accurate determinations are possible over a concentration range from 10 to 150 ng/mL of DU-717 in plasma at a relative standard deviation of 6.2%. The minimum detectable concentration is 1 ng/mL. Plasma levels of DU-717 in spontaneously hypertensive and normotensive rats following single oral administrations (10 mg/kg) have also been determined.