62304-98-7
62304-98-7 結(jié)構(gòu)式
基本信息
醋酸胸腺肽
胸腺肽A-1
胸腺阿爾法一
胸腺素Α-1
醋酸胸腺肽α1
胸腺肽(小牛)
胸腺 28 肽
胸腺肽 alpha 1
胸腺法新(胸腺肽Α1)
THYMOSIN A1
THYMOSIN APHA 1
THYMOSIN ALPHA 1
Thymosina1Acetate
ThyMosins alpha 1
THYMOSIN A1 BOVINE
thymosin α1 bovine
Thymosin α1 Acetate
THYMOSIN ALPHA1 BOVINE
物理化學(xué)性質(zhì)
對(duì)于長(zhǎng)期儲(chǔ)存，建議添加載體蛋白（0.1% HSA 或 BSA）。< br/>請(qǐng)防止凍融循環(huán)。
應(yīng)用領(lǐng)域
單雜≤1.0%
醋酸根含量5.0%～12.0%
水分含量≤10.0%
肽含量≥80.0%
常見(jiàn)問(wèn)題列表
胸腺肽 alpha 1 (Thymosinα1)是一種治療慢性乙型肝炎和增強(qiáng)免疫系統(tǒng)反應(yīng)性的藥物肽。
胸腺肽α1是一個(gè)高度保守酸多肽結(jié)構(gòu)，主要分布在胸腺組織，尤其是胸腺上皮細(xì)胞中，另外，也存在于淋巴組織(如脾、淋巴結(jié))和非淋巴組織(如肺、腎和腦)中，其分泌和釋放并不受其他激素或者釋放因子所調(diào)節(jié)。
體內(nèi)試驗(yàn)顯示，醋酸胸腺α1可以提高經(jīng)刀豆蛋白A激活后小鼠淋巴細(xì)胞白介素2受體的表達(dá)水平，同時(shí)提高白介素2的分泌水平。
醋酸胸腺α1是一個(gè)免疫調(diào)節(jié)化合物，能夠提高Thl的免疫應(yīng)答。胸腺肽α1對(duì)免疫缺陷的患者具有免疫調(diào)節(jié)作用，從而使胸腺肽α1被廣泛應(yīng)用到臨床中。
Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects.
Thymalfasin has been shown to have efficacy in multiple experimental models of immune dysfunction, mainly, infectious diseases such as hepatitis (woodchuck) and influenza (mouse), and cancer such as melanoma (mouse) and colorectal carcinoma (rat) where thymalfasin has shown antitumor effects.