65023-16-7
中文名稱
BOMETOLOL HYDROCHLORIDE
英文名稱
Bometolol Hydrochloride
CAS
65023-16-7
分子式
C25H33ClN2O7
分子量
509
MOL 文件
65023-16-7.mol
65023-16-7 結(jié)構(gòu)式
常見問題列表
生物活性
Bometolol Hydrochloride 是一種 beta-adrenergic 阻滯劑，可用于高血壓等心血管疾病的研究。靶點(diǎn)
Beta-adrenergic receptor
體內(nèi)研究
Bometolol (10-30 mg/kg, p.o.) lowers the blood pressure dose-dependently in spontaneously hypertensive rats, deoxycorticosterone and salt hypertensive rats and two kindey, one clip hypertensive rats. In subchronic study, Bometolol (10-30 mg/kg, or 100-300 mg/kg, p.o.) dose-dependently decreases heart rate, plasma renin activity, heart and kindey weitht and incidence of vascular lesion, but shows no antihypertensive effects in all the hypertensive rats.