69839-80-1
中文名稱
化合物 T24392
英文名稱
L-Glucose,2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-
CAS
69839-80-1
分子式
C9H16ClN3O7
分子量
313.692
MOL 文件
69839-80-1.mol
69839-80-1 結(jié)構(gòu)式
基本信息
中文別名
化合物 T24392 英文別名
NSC291322NSC-291322
NSC 291322
L-Chlorozotocin
L-Glucose,2-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-2-deoxy-
應(yīng)用領(lǐng)域
用途一
L-Chlorozotocin is a glucose-linked chloroethylnitrosourea with potential antineoplastic activity. Chlorozotocin alkylates DNA and proteins, induces the formation of interstrand DNA and DNA-protein crosslinks, and causes DNA strand breakage, thereby damaging DNA and resulting in cell death. This agent has been shown to exhibit antitumor and immunomodulatory effects in cell lines and animal models. Chlorozotocin is a mutagen and is less myelotoxic than other nitrosoureas.