75541-83-2
中文名稱
EXO 1
英文名稱
EXO1
CAS
75541-83-2
分子式
C15H12FNO3
分子量
273.26
MOL 文件
75541-83-2.mol
更新日期
2026/02/23 12:20:35
75541-83-2 結(jié)構(gòu)式
基本信息
中文別名
化合物EXO12- [(4-氟苯甲?；?氨基]苯甲酸甲酯
英文別名
EXO1EOX 1
NSC 214045
EXOCYTIC INHIBITOR 1
4-FLUORO-BZ-2-ABZ-OME
2-(4-Fluoro-benzoylami
Exo 1 >=98% (HPLC), solid
Exo1 - CAS 75541-83-2 - Calbiochem
2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
EXOCYTIC INHIBITOR 1
NSC 214045
EXO 1
EXO-1
EXO 1價(jià)格(試劑級(jí))
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2026/06/05 | HY-112670 | EXO 1 Exo1 | 75541-83-2 | 1 mg | 149元 |
| 2026/06/05 | HY-112670 | EXO 1 Exo1 | 75541-83-2 | 5 mg | 300元 |
| 2026/06/05 | HY-112670 | EXO 1 Exo1 | 75541-83-2 | 10 mM * 1 mL in DMSO | 330元 |
常見問(wèn)題列表
生物活性
Exo1 (2-(4-Fluorobenzoylamino)-benzoic acid methyl ester)是一種針對(duì) exocytosis 的可逆抑制劑，可誘導(dǎo) Golgi 迅速塌陷至內(nèi)質(zhì)網(wǎng)和來(lái)自高爾基體的 ADP-ribosylation factor (ARF) 1 的快速釋放。靶點(diǎn)
| Target | Value |
|
exocytosis
() | |
|
Golgi
() | |
|
ARF-1
() |
體外研究
Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC 50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.