774551-07-4
中文名稱
化合物M7594_0037
英文名稱
2-[2-chloro-4-({[2-(1H-indol-3-yl)ethyl]amino}methyl)-6-methoxyphenoxy]acetamide
CAS
774551-07-4
分子式
C20H22ClN3O3
分子量
387.86
MOL 文件
774551-07-4.mol
774551-07-4 結(jié)構(gòu)式
基本信息
中文別名
化合物M7594_0037化合物M7594_0037,10 MM DMSO 溶液
英文別名
M75940037M7594-0037
M7594_0037
M7594 0037
2-[2-chloro-4-({[2-(1H-indol-3-yl)ethyl]amino}methyl)-6-methoxyphenoxy]acetamide
應(yīng)用領(lǐng)域
用途一
M7594_0037 is a small molecule inhibitor of human peptide deformylase (HsPDF). HsPDF is an important target for anticancer drug discovery. M7594_0037 exhibits potent anticancer activities against HeLa, A549 and MCF-7 cell lines with IC50s of 35.26, 29.63 and 24.63 μM, respectively.